2480284-01-1
2480284-01-1
Chemical Structure
hCAI/II-IN-4
- CAS No.: 2480284-01-1
- Formula:C15H15N3O5S2
- Molecular Weight:381.43
IUPAC Name: cyclopropylmethyl 2-(4-sulfamoylbenzamido)thiazole-4-carboxylate
InChIKey: GNWGBZOLHBOSHB-UHFFFAOYSA-N
SMILES: O=C(C1=CSC(NC(C2=CC=C(S(=O)(N)=O)C=C2)=O)=N1)OCC3CC3
Biological Activity: hCAI/II-IN-4 (compound 6d) is a potent dual hCA I/II inhibitor with Ki values of 16.95, 15.22 and 27.04 nM for hCA I, hCA II and hCA Ⅸ, respectively. hCAI/II-IN-4 has anti-hypoxia activities and low toxicity. hCAI/II-IN-4 can be used for acute mountain sickness (AMS) research[1].
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hCAI/II-IN-4 | hCAI/II-IN-4 (compound 6d) is a potent dual hCA I/II inhibitor with Ki values of 16.95, 15.22 and 27.04 nM for hCA I, hCA II and hCA Ⅸ, respectively. hCAI/II-IN-4 has anti-hypoxia activities and low toxicity. hCAI/II-IN-4 can be used for acute mountain sickness (AMS) research. | |||||||||||||||||||||
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References
Keywords
