2483830-12-0
2483830-12-0
Chemical Structure
Ciprofloxacin-13C3,15N monohydrochloride
Synonym(s): Bay-09867-13C3,15N monohydrochloride
- CAS No.: 2483830-12-0
- Formula:C1413C3H19ClFN215NO3
- Molecular Weight:371.77
InChIKey: DIOIOSKKIYDRIQ-SBKGTBHUSA-N
SMILES: O=C1C2=CC(F)=C(N3CCNCC3)C=C2[15N](C4CC4)[13CH]=[13C]1[13C](O)=O.Cl
Biological Activity: Ciprofloxacin-13C3,15N (Bay-09867-13C3,15N) monohydrochloride is 13C- and 15N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ciprofloxacin-13C3,15N monohydrochloride | 99.9% | Ciprofloxacin-13C3,15N (Bay-09867-13C3,15N) monohydrochloride is 13C- and 15N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A). | ||||||||||||||||||||
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Ciprofloxacin monohydrochloride (Standard) | ≥98% | Ciprofloxacin (monohydrochloride) (Standard) is the analytical standard of Ciprofloxacin (monohydrochloride). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. | ||||||||||||||||||||
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Ciprofloxacin-d8 hydrochloride hydrate | Ciprofloxacin-d8 (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity. | |||||||||||||||||||||
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Ciprofloxacin monohydrochloride | 99.86% | Ciprofloxacin (Bay-09867) monohydrochloride is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin monohydrochloride exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin monohydrochloride inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin monohydrochloride induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin monohydrochloride can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity. | ||||||||||||||||||||
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References
