2489327-43-5
2489327-43-5
Chemical Structure
Trk-IN-6
- CAS No.: 2489327-43-5
- Formula:C21H21F3N6O2
- Molecular Weight:446.43
IUPAC Name: (R)-2-(4-(5-((1-(2-(2,2-difluoroethoxy)-5-fluorophenyl)ethyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)-1H-pyrazol-1-yl)ethan-1-ol
InChIKey: GYWAMONQPZXXDB-CYBMUJFWSA-N
SMILES: FC1=CC=C(OCC(F)F)C([C@@H](C)NC2=NC3=C(C4=CN(CCO)N=C4)C=NN3C=C2)=C1
Biological Activity: Trk-IN-6 shows excellent in vitro potency on a panel of TRK mutants (IC50 = 0.2-0.7 nM).
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Trk-IN-6 | Trk-IN-6 shows excellent in vitro potency on a panel of TRK mutants (IC50 = 0.2-0.7 nM). | |||||||||||||||||||||
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