2490542-33-9
2490542-33-9
Chemical Structure
Bcl-2-IN-9
- CAS No.: 2490542-33-9
- Formula:C27H31N7O3S
- Molecular Weight:533.65
IUPAC Name: 4-(2-(4-(5-((3-(4-methylpiperazin-1-yl)quinoxalin-2-yl)thio)-1,3,4-oxadiazol-2-yl)phenoxy)ethyl)morpholine
InChIKey: BPAWXOGUEIIURA-UHFFFAOYSA-N
SMILES: CN1CCN(C2=NC3=CC=CC=C3N=C2SC4=NN=C(C5=CC=C(OCCN6CCOCC6)C=C5)O4)CC1
Biological Activity: Bcl-2-IN-9 is a novel proapoptotic Bcl-2 inhibitor with IC50 value of 2.9 μM and low cytotoxic. Bcl-2-IN-9 mediates apoptosis by down-regulating expression of Bcl-2 in cancer cells and has a high selectivity against leukemia cells[1].
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Bcl-2-IN-9 | Bcl-2-IN-9 is a novel proapoptotic Bcl-2 inhibitor with IC50 value of 2.9 μM and low cytotoxic. Bcl-2-IN-9 mediates apoptosis by down-regulating expression of Bcl-2 in cancer cells and has a high selectivity against leukemia cells. | |||||||||||||||||||||
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References
Keywords
