2494000-71-2
2494000-71-2
Chemical Structure
PARP1-IN-9
- CAS No.: 2494000-71-2
- Formula:C18H21N3O5
- Molecular Weight:359.38
IUPAC Name: 5-(4-hydroxy-3-methoxy-5-(piperidin-1-ylmethyl)benzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione
InChIKey: HXNAGUIJNFUEAC-UHFFFAOYSA-N
SMILES: O=C1NC(/C(C(N1)=O)=C/C2=CC(CN3CCCCC3)=C(O)C(OC)=C2)=O
Biological Activity: PARP1-IN-9 (Compound 5c) is a PARP1 inhibitor with an IC50 of 30.51 nM. PARP1-IN-9 induces cell apoptosis and shows anticancer activity. PARP1-IN-9 has higher potency than Olaparib (HY-10162) [1].
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PARP1-IN-9 | PARP1-IN-9 (Compound 5c) is a PARP1 inhibitor with an IC50 of 30.51 nM. PARP1-IN-9 induces cell apoptosis and shows anticancer activity. PARP1-IN-9 has higher potency than Olaparib (HY-10162) . | |||||||||||||||||||||
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