2497589-76-9
Chemical Structure
Lenalidomide-Pip-butyn
- CAS No.: 2497589-76-9
- Formula:C22H25N3O3
- Molecular Weight:379.45
SMILES: O=C(C(CC1)N(C2=O)CC3=C2C=CC=C3C#CCCC4CCNCC4)NC1=O
Biological Activity: Lenalidomide-Pip-butyn is Lenalidomide (HY-A0003)-based E3 ligase ligand-linker conjugate, and is used in the recruitment of CRBN protein. Lenalidomide-Pip-butyn can be connected to the ligand for protein to form PROTACs, such as the PROTAC STAT3 degrader SD-436 (HY-169360)[1].
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Lenalidomide-Pip-butyn | Lenalidomide-Pip-butyn is Lenalidomide (HY-A0003)-based E3 ligase ligand-linker conjugate, and is used in the recruitment of CRBN protein. Lenalidomide-Pip-butyn can be connected to the ligand for protein to form PROTACs, such as the PROTAC STAT3 degrader SD-436 (HY-169360). | |||||||||||||||||||||
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Keywords