2514954-64-2
Chemical Structure
Mesoridazine-d3
- CAS No.: 2514954-64-2
- Formula:C21H23D3N2OS2
- Molecular Weight:389.59
IUPAC Name: 10-(2-(1-(methyl-d3)piperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine
InChIKey: SLVMESMUVMCQIY-FIBGUPNXSA-N
SMILES: O=S(C(C=C1N2CCC3N(C([2H])([2H])[2H])CCCC3)=CC=C1SC4=C2C=CC=C4)C
Biological Activity: Mesoridazine-d3 is the deuterium labeled Mesoridazine (HY-B1482A). Mesoridazine (TPS-23) , a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent. Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells[1].Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders[1][2].
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Mesoridazine-d3 | Mesoridazine-d3 is the deuterium labeled Mesoridazine (HY-B1482A). Mesoridazine (TPS-23) , a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent. Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells.Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders. | |||||||||||||||||||||
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Mesoridazine | 99.48% | Mesoridazine (TPS-23) , a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent. Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells.Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders. | ||||||||||||||||||||
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Keywords
