251992-66-2
251992-66-2
Chemical Structure
A-205804
- CAS 番号: 251992-66-2
- Formula:C15H12N2OS2
- Molecular Weight:300.40
IUPAC Name: 4-(p-tolylthio)thieno[2,3-c]pyridine-2-carboxamide
InChIKey: QQGWEXFLMJGCAL-UHFFFAOYSA-N
SMILES: O=C(C(S1)=CC2=C1C=NC=C2SC3=CC=C(C)C=C3)N
Biological Activity: A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases[1].
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A-205804 | 98.96% | A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases. | ||||||||||||||||||||
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