2521020-51-7
2521020-51-7
Chemical Structure
(S,R,S)-AHPC-Me-amide-C4-Br
- CAS No.: 2521020-51-7
- Formula:C28H39BrN4O4S
- Molecular Weight:607.60
InChIKey: LBUHXJMGYOPTSN-MKHKVULQSA-N
SMILES: BrCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O)=O
Biological Activity: (S,R,S)-AHPC-Me-amide-C4-Br incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-Me-amide-C4-Br can be used to design PROTAC, such as PROTAC ERK5 degrader-1 (HY-176528)[1].
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(S,R,S)-AHPC-Me-amide-C4-Br | (S,R,S)-AHPC-Me-amide-C4-Br incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-Me-amide-C4-Br can be used to design PROTAC, such as PROTAC ERK5 degrader-1 (HY-176528). | |||||||||||||||||||||
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