252725-86-3
252725-86-3
Chemical Structure
CDK9-IN-34
- CAS No.: 252725-86-3
- Formula:C18H20N4
- Molecular Weight:292.38
InChIKey: DVAXVUYGVGRJNV-UHFFFAOYSA-N
SMILES: N12C=CN=CC1=NC(C3=CC=CC=C3)=C2NC4CCCCC4
Biological Activity: CDK9-IN-34 (Compound 1b) is an inhibitor for CDK9 with an IC50 of 0.25 μM. CDK9-IN-34 exhibits cytotoxicity to cancer cell HCT116, MCF7 and K652 with IC50s of 1.43, 3.01 and 50.27 μM, respectively. CDK9-IN-34 exhibits antiviral activity against coronavirus 229E with an IC50 of 145.92 μM[1].
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CDK9-IN-34 | CDK9-IN-34 (Compound 1b) is an inhibitor for CDK9 with an IC50 of 0.25 μM. CDK9-IN-34 exhibits cytotoxicity to cancer cell HCT116, MCF7 and K652 with IC50s of 1.43, 3.01 and 50.27 μM, respectively. CDK9-IN-34 exhibits antiviral activity against coronavirus 229E with an IC50 of 145.92 μM. | |||||||||||||||||||||
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References
Keywords
