25532-03-0
Chemical Structure
N-Desmethyl clindamycin hydrochloride
- CAS No.: 25532-03-0
- Formula:C17H32Cl2N2O5S
- Molecular Weight:447.42
InChIKey: NGRDUOZWSQUFSY-XEDDUELXSA-N
SMILES: O=C([C@@H]1C[C@H](CN1)CCC)N[C@@H]([C@]2([H])[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](Cl)C.Cl
Biological Activity: N-Desmethyl clindamycin hydrochloride is the main metabolite of Clindamycin (HY-B1455). N-Desmethyl clindamycin hydrochloride shows potent cytotoxicity against L1210, KB,RPMI 6410 and RPMI 1788 cancer cells with LD50 values of 0.07, 0.29, 0.13 and 0.32 μM. N-Desmethyl clindamycin hydrochloride can inhibit cell DNA, RNA and protein synthesis. N-Desmethyl clindamycin hydrochloride can be used for the research of infection and cancer[1].
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N-Desmethyl clindamycin hydrochloride | N-Desmethyl clindamycin hydrochloride is the main metabolite of Clindamycin (HY-B1455). N-Desmethyl clindamycin hydrochloride shows potent cytotoxicity against L1210, KB,RPMI 6410 and RPMI 1788 cancer cells with LD50 values of 0.07, 0.29, 0.13 and 0.32 μM. N-Desmethyl clindamycin hydrochloride can inhibit cell DNA, RNA and protein synthesis. N-Desmethyl clindamycin hydrochloride can be used for the research of infection and cancer. | |||||||||||||||||||||
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