2573850-59-4
2573850-59-4
Chemical Structure
PW507
- CAS No.: 2573850-59-4
- Formula:C18H27ClN4
- Molecular Weight:334.89
InChIKey: RZUDJVCJZRKGCU-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(C2=NC(CN3CCCC3)=NN2C)C=C1.Cl
Biological Activity: PW507 is a potent, brain-penetrant and selective sigma 1 receptor (S1R) antagonist with a Ki of 7.5 nM for human S1R. PW507 displays a low binding affinity to S2R and hERG. PW507 can be used for the study of painful diabetic neuropathy (PDN)[1].
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PW507 | PW507 is a potent, brain-penetrant and selective sigma 1 receptor (S1R) antagonist with a Ki of 7.5 nM for human S1R. PW507 displays a low binding affinity to S2R and hERG. PW507 can be used for the study of painful diabetic neuropathy (PDN). | |||||||||||||||||||||
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References
Keywords
