26001-32-1
26001-32-1
Chemical Structure
H-Ile-Pro-Pro-OH
- CAS No.: 26001-32-1
- Formula:C16H27N3O4
- Molecular Weight:325.40
IUPAC Name: L-isoleucyl-L-prolyl-L-proline
InChIKey: FQYQMFCIJNWDQZ-CYDGBPFRSA-N
SMILES: O=C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(O)=O)=O)[C@H]([C@@H](C)CC)N
Biological Activity: H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].
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H-Ile-Pro-Pro-OH | H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE) with an IC50 of 5 μM. Antihypertensive tripeptides. | |||||||||||||||||||||
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References
- [1]. Nonaka A, et al. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertens Res. 2014 Aug;37(8):703-7. [Content Brief]
- [2]. Nakamura Y, et al. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci. 1995 Apr;78(4):777-83. [Content Brief]
Keywords
