2624181-69-5
Chemical Structure
SHP2 protein degrader-1
- CAS No.: 2624181-69-5
- Formula:C42H51Cl2N11O8
- Molecular Weight:908.83
IUPAC Name: 4-((14-(4-(((1-(6-amino-5-(2,3-dichlorophenyl)pyrazin-2-yl)-4-methylpiperidin-4-yl)amino)methyl)-1H-1,2,3-triazol-1-yl)-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChIKey: PVZCLGQITBYVPH-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCN4N=NC(CNC5(CCN(CC5)C6=CN=C(C7=C(Cl)C(Cl)=CC=C7)C(N)=N6)C)=C4)=CC=C3)=O)=O
Biological Activity: SHP2 protein degrader-1 is a potent SHP2 PROTAC degrader with an IC50 of 0.714 μM. SHP2 protein degrader-1 inhibits cancer cell growth and induces apoptosis. SHP2 protein degrader-1 can be used in cervical adenocarcinoma research[1].
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SHP2 protein degrader-1 | 98.94% | SHP2 protein degrader-1 is a potent SHP2 PROTAC degrader with an IC50 of 0.714 μM. SHP2 protein degrader-1 inhibits cancer cell growth and induces apoptosis. SHP2 protein degrader-1 can be used in cervical adenocarcinoma research. | ||||||||||||||||||||
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Keywords
