2626934-68-5
Chemical Structure
c-ABL-IN-4
- CAS No.: 2626934-68-5
- Formula:C18H11ClF3N3O3
- Molecular Weight:409.75
IUPAC Name: N-(4-(chlorodifluoromethoxy)phenyl)-5'-fluoro-2-oxo-2H-[1,3'-bipyridine]-5-carboxamide
InChIKey: FOOZIJPEYWOMDY-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C(C=C1)=O)C2=CN=CC(F)=C2)NC3=CC=C(C=C3)OC(F)(Cl)F
Biological Activity: c-ABL-IN-4 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-4 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 54)[1].
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c-ABL-IN-4 | c-ABL-IN-4 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-4 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 54). | |||||||||||||||||||||
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Keywords