2629218-24-0
2629218-24-0
Chemical Structure
SP11
- CAS No.: 2629218-24-0
- Formula:C18H19ClN2OS
- Molecular Weight:346.87
InChIKey: DGIQIBHRQRNGPY-UHFFFAOYSA-N
SMILES: CN(C(CCl)=O)CCCN1C2=CC=CC=C2SC3=C1C=CC=C3
Biological Activity: SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinson’s disease[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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SP11 | 98.91% | SP11 is a mitochondrial fission protein 1 (Fis1) inhibitor with an IC50 of 9.4 μM. SP11 binds only to activated Fis1 by engaging Cys41. SP11 preserves mitochondrial integrity and function during oxidative stress, inhibits hydrogen peroxide-induced mitochondrial ROS production, mitochondrial fragmentation, and Drp1 mitochondrial translocation. SP11 can be used for the research of parkinson’s disease. | ||||||||||||||||||||
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