2642224-22-2
2642224-22-2
Chemical Structure
Axl-IN-6
- CAS No.: 2642224-22-2
- Formula:C32H36N4O
- Molecular Weight:492.65
IUPAC Name: (S)-8-(4-isopropoxyphenyl)-N-(7-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)quinazolin-2-amine
InChIKey: SACMJOUEIQIULE-NDEPHWFRSA-N
SMILES: CC(OC1=CC=C(C=C1)C2=CC=CC3=CN=C(N=C32)NC4=CC5=C(CC[C@@H](CC5)N6CCCC6)C=C4)C
Biological Activity: Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model[1].
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Axl-IN-6 | Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model. | |||||||||||||||||||||
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References
Keywords
