2648334-36-3
2648334-36-3
Chemical Structure
HIF-2α-IN-9
- CAS. Nr.: 2648334-36-3
- Formula:C12H13F5O4S2
- Molecular Weight:380.35
InChIKey: OBDBAEQKQSFFSR-XNCJUZBTSA-N
SMILES: FC1(F)[C@@H](O)C2=C(S(=O)(C)=O)SC(OC[C@H](C)C(F)(F)F)=C2C1
Biological Activity: HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity[1].
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HIF-2α-IN-9 | HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity. | |||||||||||||||||||||
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