2650640-17-6
Chemical Structure
CDK9-IN-14
- CAS No.: 2650640-17-6
- Formula:C21H23F2N3O4
- Molecular Weight:419.42
IUPAC Name: (1S,3R)-N-(5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)-3-(2-hydroxyacetamido)cyclohexane-1-carboxamide
InChIKey: KIRQDLPHJNLSDF-GXTWGEPZSA-N
SMILES: O=C([C@@H]1C[C@H](NC(CO)=O)CCC1)NC2=NC=C(F)C(C3=CC=C(F)C=C3OC)=C2
Biological Activity: CDK9-IN-14 is a potent and selective CDK9 inhibitor with IC50 of 6.92 nM. CDK9-IN-14 has a relatively strong inhibitory effect on MV4;11 cells and in vivo tumor models, and has a good selectivity and a low toxicity and few side effects[1].
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CDK9-IN-14 | 99.91% | CDK9-IN-14 is a potent and selective CDK9 inhibitor with IC50 of 6.92 nM. CDK9-IN-14 has a relatively strong inhibitory effect on MV4;11 cells and in vivo tumor models, and has a good selectivity and a low toxicity and few side effects. | ||||||||||||||||||||
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Keywords