2653338-52-2
2653338-52-2
Chemical Structure
Thalidomide-4-O-C5-Br
- CAS No.: 2653338-52-2
- Formula:C18H19BrN2O5
- Molecular Weight:423.26
InChIKey: NAEPQESTKQLKCW-UHFFFAOYSA-N
SMILES: BrCCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O
Biological Activity: Thalidomide-4-O-C5-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C5-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-11 (HY-181306)[1].
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Thalidomide-4-O-C5-Br | Thalidomide-4-O-C5-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C5-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-11 (HY-181306). | |||||||||||||||||||||
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References
Keywords
