2653338-53-3
2653338-53-3
Chemical Structure
Thalidomide-4-O-C6-Br
- CAS No.: 2653338-53-3
- Formula:C19H21BrN2O5
- Molecular Weight:437.28
InChIKey: HGRAUYLIGAPRHU-UHFFFAOYSA-N
SMILES: BrCCCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O
Biological Activity: Thalidomide-4-O-C6-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C6-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-12 (HY-181307)[1].
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Thalidomide-4-O-C6-Br | Thalidomide-4-O-C6-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C6-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-12 (HY-181307). | |||||||||||||||||||||
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References
Keywords
