2654003-68-4
Chemical Structure
SZ-015268
- CAS No.: 2654003-68-4
- Formula:C25H38N8O3
- Molecular Weight:498.62
IUPAC Name: (S,E)-1-(4-(dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((7-isopropyl-2-methylimidazo[2,1-f][1,2,4]triazin-4-yl)amino)piperidine-1-carboxylate
InChIKey: ZWYXWBJQJPFDGB-YJJPMGAVSA-N
SMILES: CC(C1=CN=C(C(NC(CC2)CCN2C(O[C@@H](CC3)CN3C(/C=C/CN(C)C)=O)=O)=N4)N1N=C4C)C
Biological Activity: SZ-015268 is a CDK7 inhibitor with an IC50 of 23.56 nM. SZ-015268 has extremely significant anti-tumor advantages. SZ-015268 inhibits HCC70, OVCAR-3, HCT116 and HCC1806 cells proliferation with IC50s of 33, 80.56, 12.53, and 61.55 nM, respectively[1].
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SZ-015268 | SZ-015268 is a CDK7 inhibitor with an IC50 of 23.56 nM. SZ-015268 has extremely significant anti-tumor advantages. SZ-015268 inhibits HCC70, OVCAR-3, HCT116 and HCC1806 cells proliferation with IC50s of 33, 80.56, 12.53, and 61.55 nM, respectively. | |||||||||||||||||||||
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Keywords
