2664050-97-7
2664050-97-7
Chemical Structure
JAK3 covalent inhibitor-2
- CAS No.: 2664050-97-7
- Formula:C20H20N6O3
- Molecular Weight:392.41
InChIKey: RNHLEVUDVWYHSL-CQSZACIVSA-N
SMILES: [O-][N+](C1=CC=CC(C2=CNC3=NC=NC(N4C[C@H](NC(C=C)=O)CCC4)=C32)=C1)=O
Biological Activity: JAK3 covalent inhibitor-2 (compound J1b) is a selective, orally potent JAK3 inhibitor (IC50=7.2 nM) with low toxicity, anti-inflammatory activity and good bioavailability[1].
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JAK3 covalent inhibitor-2 | JAK3 covalent inhibitor-2 (compound J1b) is a selective, orally potent JAK3 inhibitor (IC50=7.2 nM) with low toxicity, anti-inflammatory activity and good bioavailability. | |||||||||||||||||||||
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References
Keywords
