2665734-13-2
Chemical Structure
PD-1/PD-L1-IN-29
- CAS No.: 2665734-13-2
- Formula:C26H24N2O6
- Molecular Weight:460.48
IUPAC Name: ((6-methoxy-2-(2-methyl-[1,1'-biphenyl]-3-yl)-1,3-dioxoisoindolin-5-yl)methyl)-L-serine
InChIKey: CUQPAAUFONWYPW-NRFANRHFSA-N
SMILES: OC[C@H](NCC1=CC2=C(C=C1OC)C(N(C2=O)C3=C(C(C4=CC=CC=C4)=CC=C3)C)=O)C(O)=O
Biological Activity: PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PD-1/PD-L1-IN-29 | 99.87% | PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity. | ||||||||||||||||||||
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