2674036-98-5
Chemical Structure
JAK3/BTK-IN-3
- CAS. Nr.: 2674036-98-5
- Formula:C22H28N8O
- Molecular Weight:420.51
IUPAC Name: 1-((2S,5R)-5-((5-cyclopropyl-2-((1-methyl-1H-pyrazol-4-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
InChIKey: RBBKSKAGLMNDCU-DZGCQCFKSA-N
SMILES: CN(N=C1)C=C1NC2=NC(N[C@H]3CN([C@H](CC3)C)C(C=C)=O)=C4C(C5CC5)=CNC4=N2
Biological Activity: JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-3 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147952A1, compound 009)[1]
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JAK3/BTK-IN-3 | JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets for autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway exhibits synergistic effects. JAK3/BTK-IN-3 has the potential for the research of JAK3 kinase and/or BTK-related diseases (extracted from patent WO2021147952A1, compound 009) | |||||||||||||||||||||
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