2676156-05-9
2676156-05-9
Chemical Structure
UNC-CA359
- CAS No.: 2676156-05-9
- Formula:C18H14ClN3O2
- Molecular Weight:339.78
IUPAC Name: N-(4-chloro-3-ethynylphenyl)-6,7-dimethoxyquinazolin-4-amine
InChIKey: KQFANGBOVPXOEP-UHFFFAOYSA-N
SMILES: ClC(C(C#C)=C1)=CC=C1NC2=C3C(C=C(C(OC)=C3)OC)=NC=N2
Biological Activity: UNC-CA359 is a potent epidermal growth factor receptor (EGFR) inhibitor, with an IC50 value of 18 nM. UNC-CA359 exhibits strong anti-tumor activity, can be used to Chordoma research[1]. UNC-CA359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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UNC-CA359 | UNC-CA359 is a potent epidermal growth factor receptor (EGFR) inhibitor, with an IC50 value of 18 nM. UNC-CA359 exhibits strong anti-tumor activity, can be used to Chordoma research. UNC-CA359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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