26989-18-4
Chemical Structure
Petiline
- CAS No.: 26989-18-4
- Formula:C27H43NO2
- Molecular Weight:413.64
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@@H](C3=NC[C@@H](C)CC3)C)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5([C@@](C[C@H](CC5)O)([H])C(C4)=O)C
Biological Activity: Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects (e.g., reducing vagal influence on the heart) by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases (e.g., arrhythmia, intestinal spasm) [1].
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Petiline | Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects (e.g., reducing vagal influence on the heart) by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases (e.g., arrhythmia, intestinal spasm) . | |||||||||||||||||||||
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Keywords
