2740278-76-4
Chemical Structure
CH-0793076 TFA
Synonym(s): TP3076 TFA
- CAS No.: 2740278-76-4
- Formula:C28H27F3N4O6
- Molecular Weight:572.53
IUPAC Name: (S)-9-ethyl-9-hydroxy-1-pentyl-1,9,12,15-tetrahydro-10H,13H-pyrano[3'',4'':6',7']indolizino[2',1':5,6]pyrido[4,3,2-de]quinazoline-10,13-dione 2,2,2-trifluoroacetate
InChIKey: MDEHNJQEYNSTCD-SNYZSRNZSA-N
SMILES: O=C1[C@](O)(CC)C(C=C23)=C(CO1)C(N2CC(C3=N4)=C5N(CCCCC)C=NC6=C5C4=CC=C6)=O.O=C(O)C(F)(F)F
Biological Activity: CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein)[1].
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CH-0793076 TFA | 98.71% | CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein). | ||||||||||||||||||||
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Keywords
