2749423-74-1
Chemical Structure
(Rac)-Atomoxetine-d7 hydrochloride
Synonym(s): (Rac)-Tomoxetine d7 hydrochloride;(Rac)-LY 139603 d7
- CAS No.: 2749423-74-1
- Formula:C17H15D7ClNO
- Molecular Weight:298.86
IUPAC Name: N-methyl-3-(2-(methyl-d3)phenoxy-3,4,5,6-d4)-3-phenylpropan-1-amine hydrochloride
InChIKey: LUCXVPAZUDVVBT-WHAGPONWSA-N
SMILES: CNCCC(C1=CC=CC=C1)OC2=C(C([2H])=C([2H])C([2H])=C2[2H])C([2H])([2H])[2H].[H]Cl
Biological Activity: (Rac)-Atomoxetine-d7 (hydrochloride) is a deuterium labeled (Rac)-Atomoxetine hydrochloride. (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively)[1].
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(Rac)-Atomoxetine-d7 hydrochloride | (Rac)-Atomoxetine-d7 (hydrochloride) is a deuterium labeled (Rac)-Atomoxetine hydrochloride. (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride. Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). | |||||||||||||||||||||
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(Rac)-Atomoxetine-d5 hydrochloride | 99.0% | (Rac)-Atomoxetine-d5 (hydrochloride) is the deuterium labeled (Rac)-Atomoxetine hydrochloride. | ||||||||||||||||||||
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(Rac)-Atomoxetine hydrochloride | (Rac)-Atomoxetine hydrochloride ((Rac)-Tomoxetine (hydrochloride); (Rac)-LY 139603) is the racemic mixture of Atomoxetine hydrochloride (HY-17385). Atomoxetine hydrochloride is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine hydrochloride is a potent Na+ channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research. | |||||||||||||||||||||
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