2750027-59-7
2750027-59-7
Chemical Structure
NTQ2494
- CAS No.: 2750027-59-7
- Formula:C29H37ClN5O2P
- Molecular Weight:554.06
InChIKey: NDKVYBNOJDCOET-DEOSSOPVSA-N
SMILES: ClC1=C(NC2=CC=C(COC)C=C2P(C)(C)=O)N=C(NC3=CC(CC[C@@H](N4CCCC4)CC5)=C5C=C3)N=C1
Biological Activity: NTQ2494 is a potent and orally active AXL kinase inhibitor with an IC50 of 4.89 nM. NTQ2494 inhibits AXL kinase catalytic activity. NTQ2494 suppresses tumor growth in mouse xenograft models. NTQ2494 can be used for the research of advanced hematological malignancies, solid tumors[1].
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NTQ2494 | NTQ2494 is a potent and orally active AXL kinase inhibitor with an IC50 of 4.89 nM. NTQ2494 inhibits AXL kinase catalytic activity. NTQ2494 suppresses tumor growth in mouse xenograft models. NTQ2494 can be used for the research of advanced hematological malignancies, solid tumors. | |||||||||||||||||||||
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References
Keywords
