2752328-62-2
2752328-62-2
Chemical Structure
EGFR-IN-27
- CAS No.: 2752328-62-2
- Formula:C35H46N9O2P
- Molecular Weight:655.77
IUPAC Name: (6-((2-((5-ethyl-2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-vinylpyrimidin-4-yl)amino)quinoxalin-5-yl)dimethylphosphine oxide
InChIKey: LUKWWQICCRFYBL-UHFFFAOYSA-N
SMILES: O=P(C)(C)C1=C2N=CC=NC2=CC=C1NC3=NC(NC4=C(OC)C=C(N5CCC(CC5)N6CCN(CC6)C)C(CC)=C4)=NC=C3C=C
Biological Activity: EGFR-IN-27 is a potent EGFR inhibitor with IC50s of <50 nM for EGFR Del, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, and L858R/T790M/C797S, respectively (WO2021249324A1, compound 511)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-27 | EGFR-IN-27 is a potent EGFR inhibitor with IC50s of <50 nM for EGFR Del, L858R, Del/T790M, L858R/T790M, Del/T790M/C797S, and L858R/T790M/C797S, respectively (WO2021249324A1, compound 511). | |||||||||||||||||||||
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