2754265-66-0
Chemical Structure
TNIK-IN-5
- CAS No.: 2754265-66-0
- Formula:C22H17N3O3
- Molecular Weight:371.39
IUPAC Name: (33R,35S,91R,92R,5S,E)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-(methyl-13C-d3)cyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-15,16,17,18-d4-35-carboxamide
InChIKey: DRHILHIKLGEWOH-UHFFFAOYSA-N
SMILES: O=C1OC2=CC(C3=CN=C(NC=C4)C4=C3)=CC=C2N1CC5=CC=CC(OC)=C5
Biological Activity: TNIK-IN-5 is an efficient TNIK inhibitor with IC50 of 0.05 μM. TNIK-IN-5 efficiently inhibits Wnt signaling in intact cells. TNIK-IN-5 shows excellent in vitro anti-colorectal cancer activity[1].
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TNIK-IN-5 | 99.75% | TNIK-IN-5 is an efficient TNIK inhibitor with IC50 of 0.05 μM. TNIK-IN-5 efficiently inhibits Wnt signaling in intact cells. TNIK-IN-5 shows excellent in vitro anti-colorectal cancer activity. | ||||||||||||||||||||
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Keywords
