2755761-70-5

PROTAC SMARCA2 degrader-24 Chemical Structure
2755761-70-5

Chemical Structure

PROTAC SMARCA2 degrader-24

  • CAS No.: 2755761-70-5
  • Formula:C45H56N10O5S
  • Molecular Weight:849.06

InChIKey: YZGBSMGPVYJEEX-VHNHUDNNSA-N

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C(C(C(C)C)C4=CC(CCN(CCN5CCN6C7=C(NC[C@H]6C5)N=NC(C8=C(C=CC=C8)O)=C7)C)=NO4)=O)O)=O)C

Biological Activity: PROTAC SMARCA2 degrader-24 (Compound 34) is a PROTAC degrader for SMARCA2 with a DC50 < 0.1 µM in HeLa. PROTAC SMARCA2 degrader-24 degrades SMARCA4 with a DC50 > 10 μM in HeLa[1].

Cat. No. Product Name Purity Description Pricing
HY-169275 		PROTAC SMARCA2 degrader-24 PROTAC SMARCA2 degrader-24 (Compound 34) is a PROTAC degrader for SMARCA2 with a DC50 < 0.1 µM in HeLa. PROTAC SMARCA2 degrader-24 degrades SMARCA4 with a DC50 > 10 μM in HeLa.
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