2756458-77-0
Chemical Structure
MAT2A-IN-7
- CAS No.: 2756458-77-0
- Formula:C17H13ClF3N3O2
- Molecular Weight:383.75
IUPAC Name: 1-(2-chlorophenyl)-3-methoxy-4-(methylamino)-7-(trifluoromethyl)-1,8-naphthyridin-2(1H)-one
InChIKey: SXJCTUGSTQFFCW-UHFFFAOYSA-N
SMILES: O=C1N(C2=CC=CC=C2Cl)C3=C(C=CC(C(F)(F)F)=N3)C(NC)=C1OC
Biological Activity: MAT2A-IN-7 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-7 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-7 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 24)[1].
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MAT2A-IN-7 | MAT2A-IN-7 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-7 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-7 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 24). | |||||||||||||||||||||
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