2757191-62-9
2757191-62-9
Chemical Structure
DS79932728
- CAS No.: 2757191-62-9
- Formula:C19H25N3O
- Molecular Weight:311.42
SMILES: NC1=NC2=CC(C3=CCN(C)CCC3)=C(OC)C=C2C14CCC4
Biological Activity: DS79932728 is an orally active inhibitor for G9a and GLP with IC50 of 12.6 nM and 75.7 nM. DS79932728 induces the production of γ-globin, thereby increasing the level of fetal hemoglobin (HbF). DS79932728 increases F-reticulocytes (F-rets) proportion and exhibits good oral absorption characteristics in cynomolgus monkey models[1].
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DS79932728 | DS79932728 is an orally active inhibitor for G9a and GLP with IC50 of 12.6 nM and 75.7 nM. DS79932728 induces the production of γ-globin, thereby increasing the level of fetal hemoglobin (HbF). DS79932728 increases F-reticulocytes (F-rets) proportion and exhibits good oral absorption characteristics in cynomolgus monkey models. | |||||||||||||||||||||
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References
Keywords
