DS79932728
Based on 1 publication(s) in Google Scholar
DS79932728 is an orally active inhibitor for G9a and GLP with IC50 of 12.6 nM and 75.7 nM. DS79932728 induces the production of γ-globin, thereby increasing the level of fetal hemoglobin (HbF). DS79932728 increases F-reticulocytes (F-rets) proportion and exhibits good oral absorption characteristics in cynomolgus monkey models.
For research use only. We do not sell to patients.
- CAS No.: 2757191-62-9
- Formula: C19H25N3O
- Molecular Weight:311.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DS79932728
MoreAll Histone Methyltransferase Isoforms
More
Biological Activity
Description
Chemical Information
-
CAS No. 2757191-62-9
-
Molecular Weight 311.42
-
Formula C19H25N3O
-
SMILES
NC1=NC2=CC(C3=CCN(C)CCC3)=C(OC)C=C2C14CCC4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
-
Journal Impact Factor
-
Most Recent
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS79932728 Related Classifications
HY-170831 Related Classifications
Powered by Bioz