2758596-07-3
2758596-07-3
Chemical Structure
BTK-IN-10
- CAS No.: 2758596-07-3
- Formula:C25H24F2N4O2
- Molecular Weight:450.48
IUPAC Name: (5-(8-amino-1-(4-(difluoro(phenyl)methyl)phenyl)imidazo[1,5-a]pyrazin-3-yl)tetrahydro-2H-pyran-2-yl)methanol
InChIKey: UCLDWTQILKQOHM-UHFFFAOYSA-N
SMILES: NC1=NC=CN2C(C3CCC(OC3)CO)=NC(C4=CC=C(C=C4)C(F)(C5=CC=CC=C5)F)=C12
Biological Activity: BTK-IN-10 is a potent BTK inhibitor with IC50s of <5 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022012509A1; example 111)[1].
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BTK-IN-10 | BTK-IN-10 is a potent BTK inhibitor with IC50s of <5 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022012509A1; example 111). | |||||||||||||||||||||
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