2758666-01-0
Chemical Structure
GLP-1R agonist 14
- CAS No.: 2758666-01-0
- Formula:C45H42F2N10O5
- Molecular Weight:840.88
IUPAC Name: 3-(1-(6-((R)-2,2-dimethyltetrahydro-2H-pyran-4-yl)-2-((S)-3-(3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-2-(4-fluorophenyl)-4-methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carbonyl)indolizin-1-yl)cyclopropyl)-1,2,4-oxadi
InChIKey: GCNDCCNSSILAEV-AHKZPQOWSA-N
SMILES: C[C@H]1C2=C(C(C3=CC=C(C=C3)F)=NN2CCN1C(C4=CN5C=C(C=CC5=C4C6(CC6)C7=NOC(N7)=O)[C@@H]8CCOC(C)(C8)C)=O)N9C=CN(C9=O)C%10=C(C%11=C(N(N=C%11)C)C=C%10)F
Biological Activity: GLP-1R agonist 14 (Compound 14) is a GLP-1 receptor agonist with an EC50 of 0-20 nM against h-GLP-1[1].
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GLP-1R agonist 14 | GLP-1R agonist 14 (Compound 14) is a GLP-1 receptor agonist with an EC50 of 0-20 nM against h-GLP-1. | |||||||||||||||||||||
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