2758802-04-7
2758802-04-7
Chemical Structure
HSD17B13-IN-12
- CAS No.: 2758802-04-7
- Formula:C18H21ClN2O3S
- Molecular Weight:380.89
InChIKey: UBEHBBQIKGJUJI-UHFFFAOYSA-N
SMILES: O=C(NCCC(C)(C)C)C1=C(NC(C2=CC(Cl)=C(O)C=C2)=O)C=CS1
Biological Activity: HSD17B13-IN-12 (Compound 3) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for both leukotriene B3 and estradiol. HSD17B13-IN-12 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI)[1].
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HSD17B13-IN-12 | HSD17B13-IN-12 (Compound 3) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for both leukotriene B3 and estradiol. HSD17B13-IN-12 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
