2758802-07-0
2758802-07-0
Chemical Structure
HSD17B13-IN-15
- CAS No.: 2758802-07-0
- Formula:C21H17ClN2O4S
- Molecular Weight:428.89
InChIKey: RCXVQOOMDKYXTH-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=C(O)C=C1)NC2=C(C(NC3COC(C=CC=C4)=C4C3)=O)SC=C2
Biological Activity: HSD17B13-IN-15 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. HSD17B13-IN-15 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI)[1].
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HSD17B13-IN-15 | HSD17B13-IN-15 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. HSD17B13-IN-15 can be used in the research of liver diseases, metabolic disorders, or cardiovascular diseases such as NAFLD or NASH, or drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
