2758802-33-2
Chemical Structure
HSD17B13-IN-31
- CAS No.: 2758802-33-2
- Formula:C21H18Cl2N2O4S
- Molecular Weight:465.35
InChIKey: BBQAVEMXEWSFJD-UHFFFAOYSA-N
SMILES: ClC1=CC(C(NC2=C(C(NCCC3=CC=CC=C3OC)=O)SC=C2)=O)=CC(Cl)=C1O
Biological Activity: HSD17B13-IN-31 (compound 32) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM and? < 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-31? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].
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HSD17B13-IN-31 | HSD17B13-IN-31 (compound 32) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM and? < 1 μM estradiol and Leukotriene B3 as substrates, respectively. HSD17B13-IN-31? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis). | |||||||||||||||||||||
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Keywords