2761181-58-0
2761181-58-0
Chemical Structure
Nav1.8-IN-7
- CAS No.: 2761181-58-0
- Formula:C22H18ClF4N3O5
- Molecular Weight:515.84
InChIKey: XMCMWJNJMLEBLY-CQSZACIVSA-N
SMILES: OC[C@@H](O)COC1=CC(NC(C(C=C(C(C(F)(F)F)=C2)Cl)=C2OC3=C(C=C(C=C3)F)C)=O)=CN=N1
Biological Activity: Nav1.8-IN-7 (Example 116) is a selective Nav1.8 inhibitor. Nav1.8-IN-7 shows an inhibition of >50% with 100 nM for Nav1.8. Nav1.8-IN-7 inhibits hERG with an IC50 of 15.6 μM. Nav1.8-IN-7 has the potential for pain research[1].
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Nav1.8-IN-7 | Nav1.8-IN-7 (Example 116) is a selective Nav1.8 inhibitor. Nav1.8-IN-7 shows an inhibition of >50% with 100 nM for Nav1.8. Nav1.8-IN-7 inhibits hERG with an IC50 of 15.6 μM. Nav1.8-IN-7 has the potential for pain research. | |||||||||||||||||||||
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