2762181-73-5
2762181-73-5
Chemical Structure
CDK/HDAC-IN-1
- CAS No.: 2762181-73-5
- Formula:C20H18N4O4
- Molecular Weight:378.38
IUPAC Name: N-hydroxy-4-((((2Z,3E)-2'-oxo-[2,3'-biindolinylidene]-3-ylidene)amino)oxy)butanamide
InChIKey: PFMKIDRZHBZULH-FTCCNZMVSA-N
SMILES: O=C(/C1=C2NC3=CC=CC=C3C\2=N/OCCCC(NO)=O)NC4=C1C=CC=C4
Biological Activity: CDK/HDAC-IN-1 shows remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively.
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CDK/HDAC-IN-1 | CDK/HDAC-IN-1 shows remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively. | |||||||||||||||||||||
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Keywords
