2762547-05-5
Chemical Structure
CD33 splicing modulator 1
- CAS No.: 2762547-05-5
- Formula:C25H25FN6O
- Molecular Weight:444.50
IUPAC Name: (R)-3-fluoro-4-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-methylpyridin-2-yl)-N-(piperidin-3-yl)benzamide
InChIKey: YTRBUPKEYPDQGD-LJQANCHMSA-N
SMILES: CC1=CN2N=CC(C3=CC=C(C=C3F)C(N([C@@H]4CCCNC4)C5=C(C=CC=N5)C)=O)=C2N=C1
Biological Activity: CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 has the potential for the research of neurodegenerative disease including Alzheimer's disease[1].
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CD33 splicing modulator 1 | 99.05% | CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 has the potential for the research of neurodegenerative disease including Alzheimer's disease. | ||||||||||||||||||||
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Keywords
