2763260-34-8
2763260-34-8
Chemical Structure
NRX-2663
- CAS No.: 2763260-34-8
- Formula:C20H13F3N2O5
- Molecular Weight:418.32
IUPAC Name: 3-(2-oxo-4-phenoxy-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamido)benzoic acid
InChIKey: QMARDTCIJVODCK-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC(NC(C2=C(C=C(NC2=O)C(F)(F)F)OC3=CC=CC=C3)=O)=C1)=O
Biological Activity: NRX-2663 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC50 of 22.9 μM and a Kd of 54.8 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NRX-2663 | 98.96% | NRX-2663 is an enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC50 of 22.9 μM and a Kd of 54.8 nM. | ||||||||||||||||||||
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References
Keywords
