2769152-95-4
Chemical Structure
DBM-GGFG-NH-O-CO-Exatecan
- CAS No.: 2769152-95-4
- Formula:C52H54Br2FN9O13
- Molecular Weight:1191.84
InChIKey: VWQCMGDWUMKTAC-NULCUTAQSA-N
SMILES: O=C(C(Br)=C(C1=O)Br)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
Biological Activity: DBM-GGFG-NH-O-CO-Exatecan (Example 4, Compound 14) is a conjugate of an ADC drug toxin molecule and a linker. DBM-GGFG-NH-O-CO-Exatecan is a complete antibody-drug conjugate intermediate that integrates a potent camptothecin-based toxin, a cleavable peptide linker (GGFG), and a reactive terminus that can directly conjugate to antibodies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DBM-GGFG-NH-O-CO-Exatecan | 96.83% | DBM-GGFG-NH-O-CO-Exatecan (Example 4, Compound 14) is a conjugate of an ADC drug toxin molecule and a linker. DBM-GGFG-NH-O-CO-Exatecan is a complete antibody-drug conjugate intermediate that integrates a potent camptothecin-based toxin, a cleavable peptide linker (GGFG), and a reactive terminus that can directly conjugate to antibodies. | ||||||||||||||||||||
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