2770246-06-3
Chemical Structure
HSD17B13-IN-40
- CAS No.: 2770246-06-3
- Formula:C23H14Cl2F3N3O3
- Molecular Weight:508.28
InChIKey: YTLGTSLZQWBCCY-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=C(CN2C=NC3=CC=CC(NC(C4=CC(Cl)=C(O)C(Cl)=C4)=O)=C3C2=O)C=C1
Biological Activity: HSD17B13-IN-40 (compound 6) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-40? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis)[1].
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HSD17B13-IN-40 | HSD17B13-IN-40 (compound 6) is a ppotent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), with the IC50 of < 0.1 μM? estradiol? as substrates. HSD17B13-IN-40? plays an important role in nonalcoholic fatty liver diseases (NAFLDs) including NASH (nonalcoholic steatohepatitis). | |||||||||||||||||||||
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Keywords