2770246-20-1
2770246-20-1
Chemical Structure
HSD17B13-IN-75
- CAS No.: 2770246-20-1
- Formula:C24H16Cl2FN3O3
- Molecular Weight:484.31
InChIKey: ORMWHZIHJJKVPV-UHFFFAOYSA-N
SMILES: OC1=C(Cl)C=C(C(NC2=CC=CC3=C2C(N(C4(CC4)C5=CC=CC=C5F)C=N3)=O)=O)C=C1Cl
Biological Activity: HSD17B13-IN-75 (Compound 21) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-75 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-75 | HSD17B13-IN-75 (Compound 21) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-75 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
