2770246-48-3
2770246-48-3
Chemical Structure
HSD17B13-IN-29
- CAS No.: 2770246-48-3
- Formula:C23H14Cl2N4O3
- Molecular Weight:465.29
InChIKey: CEDWRVDOKSMNOJ-UHFFFAOYSA-N
SMILES: N#CC1=C(CN2C=NC3=C(C2=O)C(NC(C4=CC(Cl)=C(C(Cl)=C4)O)=O)=CC=C3)C=CC=C1
Biological Activity: HSD17B13-IN-29 (Compound 53) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-29 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-29 | HSD17B13-IN-29 (Compound 53) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-29 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
