2770247-70-4
Chemical Structure
HSD17B13-IN-80-dsub>3
- CAS No.: 2770247-70-4
- Formula:C25H15D3Cl2F3N3O3
- Molecular Weight:539.35
InChIKey: VWLKLPGOFPETDX-BMSJAHLVSA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=C3C(N=C(N(C3=O)CC4=C(C=CC=C4)C(F)(F)F)C([2H])([2H])[2H])=C(C=C2)C
Biological Activity: HSD17B13-IN-80-d3 (179) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with an IC50 of <0.1 μM for Estradiol. Used in NAFLD (Nonalcoholic fatty liver diseases) research[1].
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HSD17B13-IN-80-dsub>3 | HSD17B13-IN-80-d3 (179) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with an IC50 of <0.1 μM for Estradiol. Used in NAFLD (Nonalcoholic fatty liver diseases) research. | |||||||||||||||||||||
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HSD17B13-IN-80-d2 | HSD17B13-IN-80-d2 (Compound 200) is the the deuterium labeled HSD17B13-IN-80 (HY-163263). HSD17B13-IN-80 is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-80 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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HSD17B13-IN-80 | HSD17B13-IN-80 (Compound 151) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-80 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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